Research and Thesis Projects
Our open master's & project theses are listed below.
If you have an idea for a project related to our research and would like to work with us, please contact us directly.
Automation of design and integration of sgRNAs for CRISPRi withthe Opentron system
Type: Bachelor/Master Thesis
Location: Basel
The goal of this project is to design multiple sgRNAs that modulate the gene expression of a fluorescent reporter (e.g., mCitrine), and the high-throughput creation and characterization of strains using Opentron robots and flow cytometry, respectively.
Requirements:
- Good molecular cloning skills;
- Basic knowledge of data visualization and statistics;
- Basic knowledge in Python or R.
- Experience with dCas/Cas9 is a plus, but not required.
Supervision: Arianna Candreva, Dr. Sebastian Sosa Carrillo, Dr. Andreas Cuny, Prof. Dr. Jörg Stelling.
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Development of a new, cost effective, point-of-care diagnostic (evaluation) system
Type: Research/Thesis project
Requirements: Good rapid prototyping skills (3D design & printing); Good programming skills (OOP), preferentially experience with Java and Python (C++); basic knowledge in Optics, camera sensors, image generation and processing and electronics; basic knowledge in microfluidics; basic knowledge in diagnostics; basic knowledge in statistics and experimental design.
Supervision: Dr. Andreas Cuny, Prof. Dr. Jörg Stelling.
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Development of a modular phase microscope based on TIE
Type: Master or Bachelor Thesis
Requirements: Good rapid prototyping skills (3D design & printing); Good programming skills (OOP), preferentially experience with C++ and Python; Knowledge in optics, camera sensors, image generation and processing and electronics; basic knowledge in Molecular biology and the model organism yeast; basic knowledge in statistics and experimental design.
Supervision: Dr. Andreas Cuny, Prof. Dr. Jörg Stelling.
Download More information (PDF, 55 KB)